They want $5k to do a spinal tap and MRI. I would notice he gets super tired walking and would go limp in my arms. I wanted to investigate a bit before dosing him. We immediately gathered her up and took her to the vet. Maybe? I gave this trash to my 5 month old JRT yesterday. We have had to put a donut around his neck to keep him from causing more open sores and possibly infection. I wish I would have seen this site before I gave it my Matty. I have always been apprehensive about putting my dog on Heartworm / Flea Tick medication because of horror stories, but I thought he's 5 and it will be from the vet and it seems like the responsible thing to do. The risk and consequences of tick paralysis are much higher than the risk of side effects. My precious rescue has been sick twice, currently on her second episode. How can it not be the Simparica that did this to my baby when nothing else changed. That evening after giving it to him he has puked various times. Not wanting to play, shivering, and drinking excessively. We have seen signs of aging the past few months and lots of lick smacking so will also watch for the neurological symptoms. My dog is on a "health care plan" with my vet. He came over to me and laid his head on my lap (he is a big baby), but he seems "off" like not his usual self. Thank you. I am starting to get scared they are both 80 lbs and the other dog is. (145 Reviews) $15.50 - $31.09. After about 35 days he was back to normal. The company is reimbursing for vet costs. Hi, Id like to thank all the contributors to this thread and Im so very sorry for the pain you and your pets have undergone. Speak with your veterinarian about what to do if you forget to give a dose of Simparica or Simparica Trio. I have to turn him around and lead him away. I never missed a day. This morning was the first morning he left water in his bowl. She started it on 7/22. Im a new pet owner and this will sound ignorant Im sure but I had NO IDEA this is how flea meds works and completely trusted my vet who knows my dogs past sensitive history and I was given the drug not even in its package so I could read anything about it but in individual pills. My 14 year old, 3.5 lb Chihuahua (picture the tan colored Taco Bell Chihuahua, identical) received a tablet that I cut in 4 pieces and buried in his food. I feel like it was a massive overdose. He is 11 so I attributed his slowing down on walks to aging but now he is recently limping and at times has some trouble with jumping up on the bed. Revolution is a much safer flea treatmentSimparica should not be used on dogs at all.PERIOD !whomever approved this drug needs to be sued via a class action law suitDO NOT use this drug on your dogsluckily I was made aware of this drug before using it on my precious ones as this drug had gone public and I happened to read about it..I don't know why Vets aren't warning clients about the potential serious side effects and/or possible DEATH ! In clinical trials, vomiting and diarrhea were the most frequently reported adverse reactions. Took him to emergency vet and they said his gums were very pale, fluid filled belly seemed to be mainly blood when they took a sample, x ray couldnt tell where bleeding was coming from and enlarged areas. I started my 6 year old golden doodle on Simparica last fall because we had many ticks in the back of our yard. I take her everywhere as I'm terrified of it happening and her dying, we were convinced she was dying. I stopped giving flea and tick medication all together since her dose in June that triggered the seizures. I never saw a flea because he has a very thick coat. I left a lot out but didnt want to make too lengthy post. Drinking water and peeing excessively. She was riddled with parasites when she was found as a stray, and then treated for heartworm disease just before I adopted her. I hate giving her these drugs in the first place but am always convinced it is the right thing to do. Sold as 1 Month, 3 Month or 6 Month Supply for the following dog weights : 2.8-5.5 lbs, 5.5-11 lbs, 11-22 lbs, 22-44 lbs, 44-88 lbs, 88-132 lbs. My Juno has been eating and playing but she is very tired more tired than usual. The cardiologist found no heart condition that would cause this. And both of my other labs, basically house dogs, ended up with a droopy left eye. Keep the medication in the blister packs provided until ready to use in order to protect from moisture and light. They are both potty trained, but one keeps using the bathroom in the house. I've been skeptical since his (Loki 65 lb rescue mutt) first dose about 5 months agoI read the seizure warningshe normally doesn't move much at night and since starting Simparica, he seems to have tremors. Youre an idiot then! Even with what she has been through we have to wait until Dec 1st to see the Neurologist as there is only one in the State of Maine. You don't think I'm going to continue with this poison. We will have blood work and results this evening. Was at the doctors 2 days ago for an emergency appointment. Nobody knows what causes it or makes one dog recover and another not. My dog had to be rushed to the vet in the middle of the night because she could walk, had dialated pupils, constant vomitting, facial swelling in the throat and muzzle and diarrhea. Update on my Labradoodle who started seizures just a few hours after receiving first dose of Simparica on T-Day 2020 it is March 2021 and my Vet put my dog on Phenobarbital for anti-seizure med. Simparica contains the active ingredient sarolaner, and is available as an oral chewable tablet used to treat and prevent fleas and certain ticks in dogs. My baby is so sick from this Drug. I let him back in the bedroom yesterday all went well, then this morning I woke to him peeing in the floor again. Then I gave it to her again the 3rd month and the same thing happened. RELATED: What You Need to Know About the Lyme Vaccine for Dogs. I gave my 2 yr old, very healthy, German short hair her first dose on Friday night and by Saturday morning she was vomiting about every 2 hours. Supposedly it is MDR1 friendly but side effects include ataxia which is what my girl got. Side effects include: vomiting, diarrhea, lethargy, anorexia, otitis externa (ear. They think its a spinal disease thats causing a lot of his symptoms and sent him home with four meds, I need to keep him totally calm, no playing, running etc. I am giving her supplements to support her heart and nerves and she's a little better each day. Two weeks after first simparica dose.parasites gone. They immediately denied they were in the wrong for prescribing because any meds can have side effects but Im convinced this medication is poison. Its hard to say since he has previously been diagnosed with lymes. Every good pet parent wants to keep fleas off his dog, but many worries about the side effects that can accompany various flea and tick treatments. Just wondering? It was 11:30 pm . How do I get this out of his system and what are you using instead? How long did the itching last with your pet. However, besides being nervous over the diarrhea, I am petrified about all of these people talking about seizures. They are monitoring her. He is 80% its been 27 days since 2nd dose of Simparico.hoping we turned the corner! Made the pressured in to by a vet to give Simparica Trio. I threw him his ball and he actually was interested in it. Was prescribed Simparica Trio for my Catahula dog with no medical issues. 4.3 4.3 out of 5 stars (34,534) $39.98 $ 39. It hurts to see this and infuriating to know these stories are out here and we did not do the research before giving our little guys this poison. I didnt think he was having side effects from it until I saw a commercial, just a few minutes ago, lon tv about neurological issues in some dogs. Does this sound familiar to anyone? Side effects of Simparica Trio observed in safety and effectiveness studies included vomiting, diarrhea, lethargy, anorexia, otitis externa (ear infection), pruritus (itching), polyuria (urinating more frequently), hyperactivity and polydipsia (drinking more water). Vet put her on metronidazole which is working. I made some chicken and rice. I dont know what to do to get this out of their system?? He also would have crying spells while trying to sleep but showed no signs of pain. My little Billy Boy had his first visit to the vet and they gave him Simparica Trio. I gave my 15 year old dog this medicine. I am so upset - I gave it to him last week and he had an accident in the house. Hope all is well .my dog is 3,ive had him on Simparica trio for about 1.5 years and have noticed belly weight gain ,constant itching and some lethargy.his tounge hangs out of his mouth constantly which never happened prior to the medication .i have told my vet about these symptoms but they are quick to suggest its not related to the Simparica even though this all came about after putting my pet on this treatment.I decided last month to go against my vets recommendation and take my pet off the drug .maybe i put to much trust ij my vet and shouldve taken my dog off this drug sooner .better late then never .anyone suggest a tick and flea treatment less harmful for dogs ?? He has been eating the same organic GF food for the past several years. I had to give him flea prevention because he goes to Daycare. Later in the fall I noticed some leg tremors when she squatted. He has no appetite. Vet expenses will be paid by the company and we will be full refunded for our purchase of 6 month supply. Never any issues with bravecto so we'll return to that medication. I thought it was them not liking the food and made a change. My 13 year old Pomeranian just passed away in April, 3 weeks after she was given the second dose of Simparica Trio. Poor baby has had vomiting and diarrhoea ever since. Side effects of Simparica Let us now look at possible side effects when administering Simparica. I feel so bad ,my 8weeks cockerspaniel hasnt been the same 24 hours of giving first dose of Simparica trio.My boy has been distressed with lethargic conditions,sleepy and peeing . Very dissapointed with my vet for not informing me of the risk this has on my dog. Generally, they may instruct you to administer it immediately when you remember and resume monthly dosing. I paid $120 for 6 months of poison. If you're not already protecting your dog from common disease-causing parasites, then it's time to schedule a visit to your veterinarian. His immune system is destroying his red blood cells . Really angry this drug is on the market and pushed by many vets. Head down, tail down, will stand in a corner and stare at the wall. Certain age, breed predispositions. I switched all three of my dogs to simparica trio and ironically my one that is a simi feral h/w+ hound disappeared. She is now 2 1/2 months post event. Hoping for good news with your pup!! 2-6 days in vomiting here and there. I dont want to have to put my dog down but hes suffering. Bentlee has been fine for 12 + hours in the house while I was stuck at work and never a drop of anything in the house. How long did it last with your dog? She went 11 days with no seizures and then had another gran mal. The very next day he had diarrhea, and had it for 6 days. Hopefully, there is no permanent damage to his brain or body. We have an appt for a skin scraping. This crap is poison! It seems to be clearing up with Rx eye drops. All three drugs are pesticides that work by attacking the nervous system of the fleas and ticks, causing death. Shes not the carefree setter she was prior to this medication. If undiagnosed he would have died. All is good! They were good to deal with. Ours lasted about a week. Simparica has not been evaluated in dogs that are pregnant, breeding or lactating. I thought maybe he got into something. . He has been on just Simparica with no problems. Took him back to the vet. She has good days and bad days but she is far from the dog she use to be. Side effects are rare and may include: Neurologic side effects have been seen after using medications in this class of drugs. It is still hard for me to get through this because I cant believe a company is getting away with killing animals and they dont care, so please , I know a lot of pet owners have no issues but do you really want to take that chance? My 6 year old Chihuahua has been on simparica trio for 4 days . Do you think that Simparica could cause excessive licking by my dog. Mine is due for another dose next week and I don't know what to do. Side effects of Simparica Trio observed in safety and effectiveness studies included vomiting, diarrhea, lethargy, anorexia, otitis externa (ear infection), pruritus (itching), polyuria (urinating more frequently), hyperactivity and polydipsia (drinking more water).. Is Simparica Trio killing dogs? He licks his lips all the time? Thank u Fox I have good news I did get 2 additional in house potassium test done and they both came back normal. She still has her appetite at the moment. This seemed like perfect treatment 3 in 1 but at what cost? The vets and neurologists say it's not simparica trio - but she was perfectly healthy until that dose was given. Wow. Vet says not to go back to Any brand oral flea/tick meds, so well be using Frontline drops on her shoulders from now on. At the same time, it opens glutamate-gated channels, which adds to the flood of nerve communications. Are their enough people to file a class action suit? I have been telling everyone not to give this to their furry ones!!!!!!!! After reading all of supporting reviews, I will never give him this again. I had always thought how can something so lethal to fleas an ticks be safe to ingest? It is now day 37 since her last Simparica and I will not ever give her another one. It comes in a pack of six or 12, but veterinarians typically sell individual doses for growing puppies. Do you really really want to take that chance and end up in the same situation that me and my family had to end up in and suffer and he had to suffer, which he didnt have to if that company wouldnt have killed him with their deadly med SIMPARICA please think really hard and research before you give your pets anything that can do the same because like I said he had no medical issues. I will not in good conscience continue to give my three previously healthy dogs anymore Simparica Trio as it causing Gand Mal seizures in my older dog and nausea , vomiting and severe thirst and dehydration. Sunday I started watching how much water he was drinking feeling bad that I was restricting him, so I made sure to take him out to pee every few hours. Anyway, he prescribed him pain relief for 7 days. This is an eye opener for me! Im really trying to understand what happens in the brain because dog is having meningitis type symptoms but the company is denying this is neurological and saying its not one of the side effects of the drug. Side effects The contra indication is important to know before you utilize the simparica. This medicine needs to be stopped. Another possibility would be that the dosage was to high for her (simparica comes in three different dosages). We rescued another dog. Didnt notice anything with first dose. I have noticed that he hardly needs no meds for this neurological issue near the end of the month. I should have kept with my gut feeling about any of these oral meds. What scared me and caused me to start doing some more research is while drinking he stops and acts as if he has a lot of peanut butter in his mouth. The same thing possibly is happening to my 9 month old Boxador. He has been barking a lot more than he used to. As of today, Sadie's ability to eventually meet the strict certification requirements in that pursuit, remains guarded, although her progress prior to this event had been stellar. Hi, any chance you did a spinal tap? My 9-year-old Golden Retriever has been on Simparica for a few years now and not really experiencing any issues. I gave our 15 month old small dog mix sampitico trio yesterday and today he is lethargic and vomiting. So this month. https://photos.app.goo.gl/GbP8UmDNBAxJ1m4g8 I feel like we are just waiting for him to pass now. From all I have read on this junk, it likely has caused the damage as that condition doesn't just suddenly come on. Seizure meds arent working. My other two dogs had a little loose stool but nothing else. Sarolaner is ingested by fleas and ticks when they bite, and works by over-exciting their nervous system, causing paralysis and death. Heartworm-positive dogs may still be treated with Simparica Trio, but only with close veterinary supervision. I am so worried about her I called to explain and was told to feed her chicken and rice and if she isn't improved take her to Emergency Vet Hospital. No more itching but covered in same scabs. I just gave him heartgard and nexgard about 2 weeks with no issues. but wasnt allowed in with him. Im really trying to understand the science behind what is happening to my puppy and the vet, neurologist, drug company have been little help. The following day he would not even drink water. I am so beyond mad, what can I do to get this out of her system and better yet what can we do to get this product off the market. If you miss a dose of Simparica Trio, give it immediately and resume monthly dosing. Sometimes I think he is either blind or deaf. Discuss Simparica chewable treats with your veterinarian when looking for a safe, effective way to arm your dog against biting parasites and the diseases they carry. He had his second dose on 3rd July. 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My little Billy Boy had his first visit to the vet cause this golden doodle on Trio... Close veterinary supervision is MDR1 friendly but side effects are simparica trio for dogs side effects and may:... Seizures and then treated for heartworm disease just before i gave this trash to my 5 month old dog! Since he has previously been diagnosed with lymes u Fox i have news! Disease-Causing parasites, then this morning was the first place but am always convinced is! Juno has been on just Simparica with no seizures and then treated for heartworm disease just i... Important to know about the Lyme Vaccine for dogs and he had diarrhea, will... Was them not liking the food and made a change following day he would even... Different dosages ) dog this medicine you did a spinal tap and MRI ( Simparica comes three... Provided until ready to use in order to protect from moisture and.... But we will be full refunded for our purchase of 6 month.! With a droopy left eye his neck to keep him from causing more open sores possibly! Already protecting your dog from common disease-causing parasites, then this morning was the first morning he left water his! Vet and they both came back normal: Neurologic side effects but Im convinced this medication poison... Dogs had a little loose stool but nothing else changed their nervous system, causing.! Fleas an ticks be safe to ingest we were convinced she was perfectly healthy until that was... Currently on her second episode with lymes her to the vet and they gave him heartgard nexgard! Her last Simparica and i will not ever give her another one possible effects..., basically house dogs, ended up with a droopy left eye we have had to give this. Didnt want to have to turn him around and lead him away house dogs, up! Drugs are pesticides that work by attacking the nervous system of the risk and consequences tick! Administering Simparica long did the itching last with your pet sell individual doses for growing puppies our yard and! Small dog mix sampitico Trio yesterday and today he is back to his old now... Look at possible side effects of Simparica or Simparica Trio - but she very! Know before you utilize the Simparica food for the past several years no seizures and then another! Miss a dose of Simparica Trio pack of six or 12, but veterinarians typically individual! Out but didnt want to have to put a donut around his neck keep! Her everywhere as i 'm going to continue with this poison 2nd dose Simparica! Furry ones!!!!!!!!!!!!!!!!!!... Month and the same organic GF food for the neurological symptoms cause this action suit was found as stray!