Thank you againAudrey. Im counting on Strontium Boost (and AlgaeCal Plus) to keep my bones in good shape for my, as yet, non-existent grandchildren. Hi Tyler, Now am much better, but lost 8 pts in my hips in that two year period and had a -2.5 in hip this last time. Thanks again for your help. the only Ca complex to increase bone density in adults! I am presently taking New Chapter Bone Strength Take Care. Calcium will be pulled out of our bones when our pH is to acidic to help restore pH levels to a more alkaline state. It works best for me to take AlgaeCal Plus in the morning and evening and Strontium Boost with lunch. The other night I contacted the manufacturer of my strontium and inquired as to if the supplement was better absorbed on an empty stomach or with food. Be well, Lara. Also avoid fast foods and most restaurant foods these are typically loaded with sodium chloride. The 3 Different Types of Strontium Salts You Should Know About, Myth#1: Strontium Increases Fracture Risk, Myth#2: Strontium Supplements Have Side Effects, Myth#3: Strontium Skews DEXA Results Too Much To Be Reliable. It must have been something else that upset my stomach and I am now taking all the pills with no side effects. And, of course, you can run a search for food sources of calcium and magnesium on the internet to get this information. A special form of strontium called strontium ranelate can increase bone formation and prevent bone loss when used in postmenopausal women with osteoporosis. As emphasized in Annual Reports in Medicinal Chemistry, The beneficial effects of the drug [strontium ranelate] on bone metabolism are dependent on the pharmacokinetics of strontium, not ranelic acid. Annual Reports in Medicinal Chemistry, volume 40, 2005, ed. The first serving of the Calcium supplement is then taken, around lunchtime which also includes dietary Calcium and then the second serving some six, hours later at evening meal which again includes dietary Calcium. I highly recommend it for you as well. Lara: Will this affect the absorption of the bone building products? That's true whether you have hypothyroidism (low thyroid activity) or hyperthyroidism (high thyroid activity). K2 is supposed to direct it to the bones and teeth and not the arteries. Curr Osteoporos Rep. 2006 Mar;4(1):34-9. doi: 10.1007/s11914-006-0013-6. Available data indicate that approximately 10% of the increase seen in BMD is due to strontiums larger size which also means that 90% of the increase seen in BMD is accurate. postmenopausal vertebral osteoporosisa 2-year randomized placebo controlled Since consumption of more than 1,500 mg per day of calcium is not recommended, consumption of no more than 750 mg/day of strontium is indicated. The only really good food source of vitamin A is liver, which few of us consume regularly any more (and if you do eat it, PLEASE be sure to only consume organic liver!) Hi Alma, ), Thank you for sharing your extensive knowledge about bone health and for this venue where questions can be asked! You dont have to be eating a full meal; a small snack will be sufficient. So, I have finally read the paper but I found no mention of a 170 mg dose of strontium being used. M.E.J. Your email address will not be published. We recommend speaking with your doctor to see if Strontium Boost is right for you. Hope this helps, Lara, One additional question (I just finished posting my prior questions to you.) Hi Esther, Above you describe that secondly S booster can feed unfriendly bacteria. Many thanks once again for all your answers to the questions on this blog and also for the, wealth of information in your books. If you are not consuming any dairy products, your diet is most likely providing very little if any vitamin K2, for which the best source in the western diet is cheese, particularly Jarlsberg and Emmenthaler. Hi John, The incorporation of fluoride and strontium in hydroxyapatite affects the composition, structure, and mechanical properties of human cortical bone. Dr. Orrange says that iron and calcium supplements interfere with how your body absorbs thyroid medication, so take them at least an hour apart. PMID: 20965537, Ferreri SL, Talish R, Trandafir T, Qin YX. I have family sisters with ckd. Also take Synthroid (77). Let me know how she is doing, Lara, I was taking 680 strontium citrate, 1130 calcium and 450 magnesium citrate. I understand that strontium is an element with a higher weight on the periodic table and therefore occupies more space or creates a denser appearing bone structure on a DEXA. 2012 Mar 26;12(1):12. I take a PPI for stomach ulcers which is time release and works for 24 hours. I apologize for posting my message twice. In addition to its antiresorptive activity, strontium was found to have anabolic activity in bone and thus may have significant beneficial effects on bone balance in normal and osteopenic animals. Alcohol. Just finished your book-absolutely brilliant. The immune system may react more strongly to some bacteria, such as those that cause lyme disease (borrelia burgdorferi), than others. Ranelic acid is a synthetic chemical that belongs to the same family of toxins as benzene and polycyclic aromatic hydrocarbons (PAHs). Strontium Boost can be taken with or without food (as it reads on the product label), but most folks take it right before bed on an empty stomach. Let me know about the algae cal. The information on Algaecal sounds good, but I would like to hear a recommendation fom someone besides the people selling the product. If this does not help, you should see your doctor to rule out other causes of gastritis (stomach inflammation), such as H. pylori infection or problems with your gallbladder or pancreas both of which are involved in digestion (the gallbladder secretes bile, pancreas produces pancreatic enzymes), so their dysfunction can cause nausea. If so, have you had your blood levels of 25(OH)D checked? Heartburn, stomach pain, or diarrhea; back, muscle, or joint pain; a headache, and flu-like symptoms are the most common side effects. Bone. Indeed, strontium only overestimates BMD by an average of 10%.5 So, my first question for you is, Are you taking your AlgaeCal Plus & Strontium Boost on an empty stomach? Do you take a multivitamin as well? My neurologist couldnt find a cause but I havent started back up yet. Dr. said to increase VitD another 100o and I did. The bottom line here: To err on the side of safety, I would not recommend the use of strontium citrate in young, premenopausal women. Seemingly in Europe every time they move wheat from country to country they spray it with insecticide and of course you can imagine what that does to your system. Bottom Line for best absorption, take strontium separately from other minerals. Hello! But 3 hours afer eating a bit of yogurt as part of a fruit dessert should not be an issue. Were sorry to hear youre experiencing fatigue while taking our products. Strontium (Citrate) is an alkali earth metal, very similar in structure to Calcium, and has a similar effect in the body. Synthroid is FDA pregnancy category A - it is definitely secure for breastfeeding Synthroid or Levothyroxine in its generic form, is a a commonly used medication to treat Hypothyroidism, an underactive thyroid. as this happens from time to time. A member of the American Medical Writers Association for more than 25 years, Lara publishes and reviews articles covering breaking research on bone health in Integrative Medicine: A Clinicians Journal. Peng S, Liu XS, Huang S, et al. There's a lot of misinformation in the posts above. Mary. Be sure to take it when you are NOT also taking calcium or consuming calcium-rich foods. I eat it frozen!!! This is what your body is telling you! Thank you in advance for your help. If high blood calcium levels are present, there are a number of tests she should consider and discuss with her endocrinologist these can all be found in 2nd edition of Your Bones in the 30 page long Lab Tests appendix. In Your Bones, Ive laid out how you can figure out what you are getting from your diet and then what the supplement options are, so you can better determine what you need. To me it seems to show, over a 5 year period, bone on strontium aging and becoming more infused with calcium and phosphorous and less with strontium. Sr21 is taken up into bone by two different mechanisms: (1) an initial rapid mode, depending on osteoblastic activity, which is eventually saturated, and whereby Sr21 is taken up by ionic exchange with bone Ca21, binding of Sr21 to preosteoid proteins, or combinations of these; and (2) a second slower mechanism involving the incorporation of Sr21 into the crystal lattice of the bone mineral. Has any research been done to show the safety of using strontium citrate for years? 2017 Feb;105(2):433-442. doi: 10.1002/jbm.a.35917. I do take adequate amounts of calcium, magnesium and vitamin d3. BMD in my hip/femur had gone up 3.5% and was up 6% in my spine. I very much hope this information will be helpful for you. I am now taking Algaecal for about a month. For ease and convenience, most people take their Strontium Boost at night right before bed. (I have a copy of your last book and have read it from cover to cover.) He asked me to take for 6 months this Strontium Renalate suspension every year. The only issue I have ever heard even anecdotally mentioned re MK-7 is that one woman wrote me that it gave her so much energy, she had trouble sleeping; she has to use MK-4, which clears out of the body much more rapidly than MK-7, for which reason, an effective dose of MK-4 is 45 milligrams per day! They ALL returned to the exercise program and completed a modified regimen without problems. Here are a couple of the most recent: Angle SR, Sena K, Sumner DR, Virdi AS. Detailed analysis indicates that many transporters (such as PepT1, SGLT-1, GLUT5, MRP2, NT2, and high affinity glutamate transporter) share similar expression levels in both human and rat with regional dependent expression patterns, which have high expression in the small intestine and low expression in the colon. I have read your book,Your Bones and not really found a specific answer to this question . Thanks! Her range was almost 2,000 ng/ml ( which she indicated was over 4,000 higher than normal). Hi Lara, Note that the COMB study was conducted by Dr. GenUIs (not Genius)I have contacted his office regarding the type of exercise that was used by patients in the study and was surprised to learn that he recommends jumping, running, or jogging (exercises that are typically contraindicated for osteoporotic patients), working up to 300 repetitions. In adult bone, our model is based on the impact of changes in the bone remodeling rate on the degree of mineralization of bone tissue. Is there any validity to this statement? Luckily, strontium has science to back it up and someone (i.e. Maybe its just me. 2001 Sep;69(3):121-9. Hi Patricia, Youre so welcome! Hi Tyler can you send me the PMID #s for this study, so I can pull the full paper and see what exactly was done and the full results? However, I just read a site from Dr. Peter Dobias about how its dangerous to give them to your dogs due to the strontium levels from Fukushima. Here s a link to Dr. Grouts website: http://www.arizonaadvancedmedicine.com The other two Plans also used AlgaeCals plant calcium, but in differing amounts (750 mg in Plan 2, 756 mg in Plan 3), and with differing amounts of vitamin D3 ( 1,000 IU in Plan 2; 1,600 IU in Plan 3) and other bone health ingredients. Strontium citrate, however, has never been found to cause this or any of the other ADRs produced by strontium ranelate. Expect results will be good. I also discuss bone building exercises and diet. Dont know where to start? Will the trace minerals in AlgaeCal be enough on a daily basis or do I need to supplement? Patients were randomized to receive placebo, 0.5 g, 1 g, or 2 g SR/d for 2 yr. And your BMD score will also be impacted if the technician running your scan does not place your body exactly as it was placed on your prior scan. It is extremely important that you are consuming optimal levels of vitamin K both as K1 (phylloquinone) AND as K2 (menaquinone). I take a PPI for stomach issues. vertebral fracture in women with postmenopausal osteoporosis. In the U.S., Canada and Europe, the typical diet contains 24 mg strontium/day. I am 57-years-old. Thus, for 71% of the participants in this study, a short daily period of exercise, a few minutes of which was high impact exercise, was a reasonable and safe recommendation. I was wondering if you had seen this article from Univ of Toronto, re lyme (borrelia burgdorferi) causing bone loss? Cannata, J., Balogh, A., Lemmel, E. M., Pors-Nielsen, S., Rizzoli, R., Genant, H. So the range of overestimation here is 6.3% to 11.2% of the % of improvement in BMD. I use it because it works. How quickly our kidneys filter creatinine from the bloodstream, which is called the creatinine clearance rate, provides a measure of how effectively your kidneys are filtering your blood. I learned so much! Best Strontium Citrate. I am happy to suggest some choices of natural strontium supplements for you. Feel free to use the information as you need ? At this point, youre probably wondering. Our correspondence has been a total delight for me. PMID: 15329809 [PubMed indexed for MEDLINE] Free full text. Heres the 2004 paper that came up when I ran a PubMed search for Meunier PJ: Med Sci (Paris). Many people need 5,000 IU of vit D3 daily to achieve these levels. Here is the link: http://orbi.ulg.ac.be/bitstream/2268/7937/1/The%20Effect%20of%20strontium%20ranelate%20on%20the%20risk%20of%20vertebral%20fracture%20in%20women%20with%20postmenopausal%20OP.pdf, Here is his 2002 article which is the one being cited. My PCP ran some blood tests in September at my request, Vit D, 25-Hydroxy was 35.4, my calcium and PCH was 9.3 and 58. Thanks for sharing and we hope you enjoy some of our other blog articles ? In terms of this small an amount of strontium having beneficial effects on bone as well as teeth I have not seen any research indicating this low a dose would be beneficial in bone. MK-4, even at such a low dose, cant hurt and may help. However, you may have heard some less-than-confidence inspiring things about strontium. I bought some and was determined to eat it regularly. Cost for the Kindle version is around $7, and I think the print version is being sold on Amazon for around $9. As you mentioned, certain medications (including nonsteroidal anti-inflammatory drugs like aspirin or ibuprofen) can trigger lymphocytic colitis. PMID: Kombucha is another excellent dairy-free source of pro-biotics. Epub 2005 Sep 29.PMID: 16195514 Hi Shane, No worries! This being said we must ALWAYS trust our own bodies when our personal results dont match up with the research no matter how august and respected the medical journals or how many studies have been published showing something that our own unique body is not agreeing with! In postmenopausal osteoporotic women treated with SR (0.5, 1 and 2 g/day) for 2 years, Sr was dose-dependently deposited into new bone without changes in the degree of mineralization of bone tissue. Obviously, strontium-89 is not strontium citrate, but Ive provided a couple of the references on this below if youre interested. Oh myso sorry I didnt read the fine print.it was right there! Both minerals share a common carrier system in the intestinal wall, which will always choose to transport calcium rather than strontium from our digestive tract into our bloodstream. Outside of 2 studies conducted more than 50 years ago in which WAY more strontium was consumed along with virtually no calcium and ricket-like bone malformations occurred, the only adverse health effects noted in the peer reviewed medical literature with strontium are seen the patented drug version, strontium ranelate, which significantly increases risk for VTE and DRESS syndrome plus a number of other unpleasant but less deadly effects. i do notyetstill egfr in 80s. https://www.mayoclinic.org/diseases-conditions/thumb-arthritis/symptoms-causes/syc-20378339 Unfortunately, as we age, cumulative damage to our joints over the years, particularly when low levels of chronic inflammation are present (which also promote bone loss), starts to show up. Regarding boron, this trace mineral is also definitely needed. Thanks! Esomeprazole magnesium may increase the levels of saquinavir in your body. Or you could have become sensitive to some component in your food. No studies have shown any adverse effects. Dr. Wright recently commented to me that he thinks it best to start out with 680 mg of strontium citrate daily, but then to drop down to half this dosage or even a bit less once good results have been achieved. Are you currently taking supplemental strontium? In the most recently published studies in which the effects of natural strontium salts on bone health were researched, strontium citrate was effectively absorbed and deposited in bone at both a 340 mg per day and a 680 mg per day dose. Magnesium (as Amino Acid Chelate) 75mg If you have a copy of Your Bones, please check the section on calcium where I have provided a table showing the best food sources of calcium (p. 207 in the book) along with how much calcium is present in a typical serving of each food. Re strontium I have not heard of its causing diarrhea (sorry, less delicately phrased), but the first rule, ALWAYS, is to trust YOUR own body and its reactions to anything recommended. Association between DHEAS and bone loss in postmenopausal women: a 15-year longitudinal population-based study. Please help me. In men, a small loss is detected in 40-year olds, which increases to a loss of about -0.8% per year into old age. Click on any of the subcategories below to jump to that section: Strontium is a mineral from the earth that is naturally found in your body in small amounts. You were correct. The only way to know what YOU need is to run the blood test for 25(OH)D and see what your levels are optimal level is considered to be 60-80 ng/mL. In this book, I go over all the many factors that can contribute to bone loss that you may not be aware of, every nutrient your bones need to build, how to determine if you are getting enough from your diet and how to choose a supplement if you need more. Glad you enjoyed the information, Kalpana! I believe these are open to the public. If your kidney function is normal, then this is not an issue for you. Hi Kathy, Try this and your taste buds as well as your digestive tract and bones will be delighted with you. Can this be whats going on? Re #2, following are the citations of a few of these papers (all are available on PubMed) with my italics added for emphasis and my comments on the relevant text: Certain medications want you to either take or avoid taking on an empty stomach. Aquamin is a different species of algae from Algas Calcareas. Although my bones have now been in excellent shape for several years (I was still osteopenic when I began taking AlgaeCal Plus & Strontium Boost, which fully restored the health of my bones after just 6 months), I continue to take Strontium Boost as well as AlgaeCal Plus to ensure my bones remain strong and healthy. I have read several good stuff here. Personally, I had stopped taking Strontium Boost a couple of years ago because my bones are in such good shape now, at age almost 69, that I didnt think I needed the extra help. I also take WP which is similar to Armour. 2005 Nov;95(11):2049-56. Most of us eat the same foods over and over and do not vary what we eat all that much. Normal results from this test range from 10.0 45.0 ng/ml. That currently is only possible after removing the bone, ashing it and chemically analyzing the minerals. Lara: To regulate my INR levels I have to be careful with vitamin k. Is strontium citrate safe for me? Citrate is a favorite food of unfriendly bacteria. Shouldnt the label reflect the actual percentage? One other suggestion we order our fish from Vital Choices (www.vitalchoices.com) You can look at their website, see their products and their excellent quality control. used a more aggressive exercise program. Yes, DHEA supplementation is a very good idea. Gan To Kagaku Ryoho. 2015 Mar;29(3):607-8. doi: 10.1111/jdv.12407. So to me you are like an angel. Supplements should always be taken with food, both to provide a buffer if your stomach acid production is good and to trigger sufficient stomach acid production if your ability to produce stomach acid has begun to decline. I definitely understand that you wouldnt want to lose any hair! Really when I dropped this message at your blog I did not even have 1% hope that someone would reply me in reality, since morning I am smiling feeling good about my health and sharing this fantastic story of a long distance medical help to everyone at office and family. It is an issue for individuals with chronic kidney disease. An acidic pH, which many of us typically have because we eat the standard Western diet, contributes to bone loss. M. Hi Marilyn, I suggest you ask the folks making these claims for references in the medical journals in which research has been published confirming them, and if they cannot supply you with any, do not give them any credence. I hope this will fully clear up your confusion, and now that AlgaeCal is aware of the potential for misunderstanding, steps can be taken to make the label on Strontium Boost easier to understand correctly. abkeeffdkekd. Strontium has nearly twice the atomic weight of calcium. Items left from my list of meds: Super Ubiquinol CoQ10 from LEF, Zinc 22 mgm, Chromium 50 mcg, daily and copper 2mg twice a week; manganese is picked up from CA/Mg supplement. Here are links to this research (I see only one of the papers I cited is now provided as a link in the post on AlgaeCal.com. I was taking Fasomac for three years with the doctors advice. can I take just the AlgaeCal without Strontium? Hi Jeanette, At age 48, you are perimenopausal. Why? AlgaeCal is a pure algae product / for Aquamin, *80% of material brought on to the large dredgeing ship is discarded as impure K. Niu, R. Ahola, H. Guo et al., Effect of office-based brief high-impact exercise on bone mineral density in healthy premenopausal women: the Sendai Bone Health Concept Study, Journal of Bone and Mineral Metabolism, vol. I found NOF, and actually they did a good job of alarming me. Problems were minor and did not prevent any of the women from continuing to exercise although for a few of these women, their program were modified to meet the individuals needs. How does it compare to the AlgaeCal that you recommend? Youll understand why strontium works as it does when you read the list of strontiums bone-building effects on both osteoblasts and osteoclasts. For example, if you gained a modest 1% after taking strontium and you reduce that score by 10%, you STILL GAINED .9% of new bone. AlgaeCal is clinically Supported for bone health: Calcif Tissue Int. As you know, shortly after maximal bone mass has been accrued (early to mid-30s), women start losing 0.5-1% of their BMD annually, a loss that accelerates to 2% or more during menopause and continues for as many as 10 years afterwards. I have a smoothie for breakfast that contains a bunch of kale. Humans absorb about 25-30% of the elemental strontium consumed when it is administered alone. One paper (Novel strontium fortified calcium salt for enhancing bone formation As in vitro and in vivo large animal model study.) AP/SB, as the research shows (3rd study), can turn this around even in postmenopausal women losing at least 2% or more annually. I read your research about the strontium ranelate vs. sc.from a post in 2010. I have written some blogs for them discussing research related to bone health and have been compensated for this e.g., my blog on the issues surrounding strontium or the blog I recently wrote on the potential dangers of fluoride. Also, you want to consume approximately twice as much calcium (from food and supplements) as strontium. I reread my post this morning before I read yours. If you feel nauseous, you can take it with a small snack, but if you can wait until an hour after taking it to eat, that's best. Vitamin D increases our bodys ability to absorb calcium; vitamin K2 activates the proteins responsible for putting calcium into bone (osteocalcin) and keeping it OUT of arteries, kidneys, breasts. Expression profiles of transporters and metabolizing enzymes in both rat and human intestines (duodenum and colon) were measured using GeneChip analysis. It is true that calcium and strontium compete for absorption and calcium will win out in this competition, so maximum benefit from stontium will occur when large doses of calcium are not being ingested at the same time. Long-term studies in rats confirmed pronounced dose-related increments in trabecular bone volume, mineralised bone volume, osteoblastic surface, and a reduction in osteoclast number, but osteoid thickness was not affected., Dahl SG, Allain P, Marie PJ, et al. If it does replace calcium, where does the 1200 mg of calcium go? The more bacteria present, the greater the rate of bone loss.. I am Canadian and the BMD test shows lumbar spine T-score of -2.8 and Femoral neck T-score of 1.8 I took Calcitonin Nasal spray for two years and apparently my bone loss has continuednow I have stopped Calcitonin altogether and I am looking for something else. I wish it were less complicated, and we could all just do exactly the same thing, and it would be just right for each of us but this is not how it is. This level may be excellent and may simply be indicating you are effectively absorbing strontium. I take the Nutralife Calcium with VitD3 and VitK. No adverse effects. Sorry that I have not been able to find it on PubMed. Inspired by her family history of osteoporosis and her own battle with low bone density, Lara Pizzorno has devoted more than thirty years to researching how to prevent bone loss and restore bone health. MK-4 at a small dose is unlikely to be all that helpful, but should not be harmful either. Dont be fooled by the strontium critics. Injection-site reactions (such as redness or swelling around the injection site) are common with Boniva injections. If you havent read it, please consider doing so. I have learned quite a bit about strontium citrate, including how/when to take it. OK to your questions: -2.4 rt. So I made the assumption that the formula was strontium di-calcium phosphate (in which case the molar mass=357.7 g/mole). Re your vitamin D levels, which your last blood test showed were too low (you want to be between 60-80 ng/mL), since you are lucky enough to be living in the Phoenix area, if you are not already doing this please get outside for at least a half hour sometime between 12pm and 2pm and get some sunshine on your skin (no sunscreen!). Remember, the women were not taking calcium supplements, just getting their calcium via the foods in their normal diet, so not restricting the time during the day when they took their strontium citrate also seems reasonable. The key to safety long term is ensuring calcium intake from diet and supplements is at least twice that of strontium. That said, your suggestion is a good one and I will keep a diary for a couple of weeks and see if something turns up. Lastly, re bio-identical hormone replacement. Copy of your last book and have read it from cover to cover. loss when used in postmenopausal with. 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